The outcomes of intravitreal C3F8 gas tamponade combined with laser photocoagulation treatment for optic disc pit maculopathy.

Gunsu Deniz Mirza,Hurkan Kerimoglu,Enver Mirza,Gunhal Satirtav

doi:10.1007/s10792-021-02179-0

Gunsu Deniz Mirza, Hurkan Kerimoglu + Show 2 more

Open Access

https://doi.org/10.1007/s10792-021-02179-0

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Journal: International ophthalmology	Publication Date: Jan 28, 2022
Citations: 3	License type: NO-CC CODE

Affiliation: Necmettin Erbakan University

Abstract

PurposeTo share the anatomical results and visual outcomes of intravitreal gas tamponade combined with laser photocoagulation treatment for optic disc pit maculopathy (ODPM). MethodsIntravitreal gas tamponade combined with laser photocoagulation treatment was performed on six consecutive patients with ODPM. A 0.3 mL of 100% perfluoropropane (C3F8) gas was injected intravitreally. The patients were then asked to maintain prone position until the C3F8 gas disappeared. Laser photocoagulation was performed the day after the procedure. The outcomes were determined by spectral-domain optical coherence tomography and best-corrected visual acuity (BCVA).ResultsIn the present study, visual improvement and reduction in serous macular detachment were observed in 83% of the ODPM patients. Complete retinal reattachment was achieved in 66% of the ODPM patients. In one patient, no regression was observed after the repeated treatment, and pars plana vitrectomy was performed. The final BCVA improved in five eyes and unchanged in one eye. No postoperative complications were observed during the follow-up period in any patient.ConclusionsIntravitreal C3F8 gas tamponade combined with laser photocoagulation procedure is an effective, minimally invasive, and cost-effective treatment method for ODPM.

Highlights

Optic disc pit (ODP), which was first described by Wiethe in 1882 [1], is a congenital cavitary anomaly of the optic disc [2]
Intravitreal C3F8 gas tamponade combined with laser photocoagulation procedure is an effective, minimally invasive, and cost-effective treatment method for ODP maculopathy (ODPM)
ODP is generally asymptomatic, but serous macular detachment develops in 25–75% of patients which is termed as ODP maculopathy (ODPM) [5]

Summary

Introduction

Optic disc pit (ODP), which was first described by Wiethe in 1882 [1], is a congenital cavitary anomaly of the optic disc [2]. It is a rare condition with an estimated prevalence of 1 in 11.000 patients [3]. Visual deterioration or vision loss is the most common initial complaint of the patients. ODPM may occur during childhood, but it is most common between second and fourth decades of life [6]. The pathogenesis of ODPM remains unclear, but there are several hypotheses including liquefied vitreous entering through the ODP, cerebrospinal fluid entering from the subarachnoid space through the ODP, and leakage from blood vessels at the ODP or the choroid about the origin of fluid seen in the intraretinal and subretinal spaces in the literature [7]

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