Abstract
Objective:The aim of the present study was to evaluate the pregnancy rates of intrauterine insemination (IUI) and controlled ovarian hyperstimulation (COH) in patients with one-sided tubal occlusion on hysterosalpingography (HSG).Materials and Methods:Patients who underwent COH/IUI were enrolled into this retrospective cohort study. The patients with one-sided tubal occlusion diagnosed under HSG who met the inclusion criteria were accepted into the study group. The control group consisted of patients with unexplained infertility. The outcomes of COH/IUI were compared between the study and control groups.Results:Ninety-seven patients in the study group (n=44) and control group (n=53) who underwent COH/IUI treatment were included into study. The biochemical, clinical, and ongoing pregnancy rates were similar between patients with unilateral occlusion diagnosed under HSG and those with unexplained infertility. The spontaneous pregnancy rate within one year was higher in patients with normal HSG than in patients with unilateral tubal occlusion, but the difference did not show statistical significance.Conclusion:Infertile patients with one-sided tubal occlusion in HSG can be managed as with patients with unexplained infertility and normal HSG findings. In addition, COH/IUI may be considered as the first-line treatment option in the management of these patients.
Highlights
Tubal disease is responsible for approximately 30-40% of female infertility[1]
controlled ovarian hyperstimulation (COH)/intrauterine insemination (IUI) may be considered as the first-line treatment option in the management of these patients
We aimed to evaluate the pregnancy rates of COH/IUI in patients with unilateral tubal occlusion diagnosed under HSG
Summary
Tubal disease is responsible for approximately 30-40% of female infertility[1]. Hysterosalpingography (HSG) and laparoscopy are the most common procedures used in the assessment of the tubal patency. There is no consensus about the optimal management of patients with unilateral tubal occlusion. The assessment of tubal patency through laparoscopic chromotubation, intrauterine insemination with controlled ovarian stimulation (COH), and in vitro fertilization (IVF) are the recommended management options for these patients[4,5,6]. There are insufficient data regarding the success rates of COH and IUI in the treatment of patients with unilateral tubal occlusion. We aimed to evaluate the pregnancy rates of COH/IUI in patients with unilateral tubal occlusion diagnosed under HSG
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