The outcomes and risk factors of early reoperation after initial intestinal resective surgery in patients with intestinal Behçet's disease.

Abstract

Patients with intestinal Behçet's disease who underwent intestinal resective surgery often require reoperation. However, there have been no studies on the risk factors and outcomes of early reoperation in these patients. We retrospectively evaluated 41 patients with intestinal Behçet's disease who received repeated intestinal resective surgeries between 2006 and 2016. We analyzed two different patient groups-those who required early reoperation within 6months and those who underwent reoperation >6months after the initial surgery-and determined the risk factors for early reoperation. Eleven patients (26.8%) underwent reoperation within 6months and 30 patients (73.2%) after 6months. Emergency surgery at the initial operation and higher initial perioperative erythrocyte sedimentation rate and C-reactive protein levels were significantly associated with early reoperation in the univariate analysis. After the multivariate analysis, initial emergency operation (P=0.020; hazard ratio [HR], 42.625; 95% confidence interval [CI], 1.817-1000.088) and high erythrocyte sedimentation rate (P=0.039; HR, 1.049; 95% CI, 1.002-1.097) were determined to be the independent factors for early reoperation. Emergency surgery and high perioperative erythrocyte sedimentation rate levels were the prognostic factors for early reoperation (within 6months) in patients with intestinal Behçet's disease after initial bowel resective surgery.