Abstract
Objective. To establish the origin of the purulent complications developing in obturative ileus in experiment.
 Materials and methods. The experiment was conducted on 24 white rats of the Wistar line, in whom obturative ileus was simulated.
 Results. The data about dynamical changes of the intestinal wall histostructure above the obstruction and concerning its seeding degree were obtained. In 12 h from the obstruction occurrence the destructive changes in intestinal wall, consisting of mucosal phlegmonous inflammation, occurr, while the bacterial seeding level of the intestinal wall raises from 104 CFU/g of the tissue (the initial) up to 1011 CFU/g. In 36 hours of the ileus persistence the purulent inflammation spreads on submucosal and muscular layers, and translocation of microflora into submucosal layer occurs, the level of microbial seeding of intestinal wall in these terms raises up to 1010-1011 CFU/g of the tissue.
 Conclusion. Phlegmonous enteritis develops in durable persistence of obturative ileus in intestinal wall, localized above the obstruction. After elimination of obturative ileus, the intestinal lumen and abdominal cavity sanation the main origin of purulent complications persists in intestinal wall above the obstruction.
Highlights
To establish the origin of the purulent complications developing in obturative ileus in experiment
The experiment was conducted on 24 white rats of the Wistar line, in whom obturative ileus was simulated
In 12 h from the obstruction occurrence the destructive changes in intestinal wall, consisting of mucosal phlegmonous inflammation, occurr, while the bacterial seeding level of the intestinal wall raises from 104 CFU/g of the tissue up to 1011 CFU/g
Summary
Источник гнойно–септических осложнений при обтурационной непроходимости кишечника Через 36 ч существования илеуса гнойное воспаление распространяется на подслизистый и мышечные слои, происходит транслокация микрофлоры в подслизистый слой, уровень обсемененности стенки кишки в эти сроки достигает 1010–1011 КОЕ/г ткани. Санации просвета кишки и брюшной полости основным источником гнойных осложнений является стенка кишки выше места препятствия.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
