Abstract

Of the many suggestions brought forward with regard to the chemistry of the process by which the hydrochloric acid of the gastric juice is produced, one by Maley1 has certain things in its favor which cannot be said of the others. This relates to the interaction of disodium phosphate and calcium chloride with the production of hydrochloric acid and tricalcium phosphate. Probably what really takes place when solutions of these are mixed, is the formation of acid Ca phosphate which hydrolyzes rapidly at room temperature to form a basic calcium phosphate and an acid phosphate containing more phosphoric acid than the monophosphate. The latter may be considered to act upon the calcium chloride with production of free hydrochloric acid. Maley showed that free HC1 could be dialyzed from such a mixture, which we have confirmed also by distillation with or without the addition of manganese dioxide. In the former case abundant chlorine is liberated. Fatal objections to the theory in its original form are that there...

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