Abstract

Opiomelanotropinergic cells in the intermediate lobe of the pituitary and in neurons in the brain secrete at least 7 peptides related to melanocyte stimulating hormone (MSH) and β-endorphin (BE). This paper reviews the anatomy, physiology and biochemistry of opiomelanotropinergic neurons and discusses the implications of multi-neurotransmitter and multi-hormone neurons and cells.

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