Abstract
SUMMARY Histological examination (azan method) of the islets of Langerhans of the chick embryo showed that β cells were present on the 11–12th day of incubation, but it was difficult to be certain that granules were present in the cells on those days. An occasional granulated β cell could be seen on the 12th day but granulation became general by the 16th day. Histochemical tests (by the Barrnett & Seligman technique) indicated the presence of protein-bound sulphydryl groups in the β cells from the 14th day of incubation onwards. Bioassays of the pancreas by the rat diaphragm method showed that insulin was, in fact, present from the 12th day of incubation onwards. There is no evidence for the presence of insulin in egg yolk, since yolk extracts did not enhance the glucose uptake of rat diaphragm. Alloxan did not inhibit the development of β cells in the pancreas of chick embryos.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
