The ontogenesis of skin and organ characteristics in the Syrian golden hamster: II. Body and organ weights as well as blood glucose and plasma insulin levels

Abstract

The ontogenesis of the organ weights of the liver, kidneys, adrenals, testes and ovaries as well as the blood glucose and plasma insulin levels were studied in a total of 464 golden hamsters of both sexes of the acromelanic white inbred strain Bio 1.5 and agouti coloured outbred strain Han:AURA. Familial and seasonal influences were excluded by means of randomisation (25 groups from 1-365 days of life). Body weight development was found to be sigmoid and showed significant differences in terms of age, sex, and strain. Liver and kidney weights developed in parallel. Here, too, strain differences (agoutis greater than acromelanics) were seen, and sex differences were observed in the case of the kidneys (females greater than males). The increased adrenal weight in male hamsters compared to females was in accordance with species- but not rodent-typical behaviour. Both the testes and ovarian weights varied considerably. Age as well as, in part, strain differences were seen in the case of the blood glucose and insulin levels. The continual development of body and organ weight could be explained in terms of physiological changes.