Abstract

Cognitive enhancing drugs are claimed to improve cognitive functions such as learning and attention. However, little is known presently about the characteristics of off-prescription cognitive enhancing drug users or their perceived everyday experience with these drugs. As modafinil is the most commonly used off-prescription cognitive enhancing drug, the current study aimed to provide a detailed profile of modafinil users and their experiences and perceptions of this drug. To this end, an online survey, targeting cognitive enhancing drug users and students, was advertised on forum sites. Information was obtained regarding demographic data, illicit drug use, psychiatric diagnosis and experience of modafinil. Of the 404 respondents, 219 reported taking modafinil. Of these the majority were male, American or British, university-educated and currently employed, with a mean age of 27. Overall, modafinil was perceived by users as being safe. Modafinil users reported higher levels of illicit drug use and psychiatric diagnosis than would be expected from population-based data. More frequent reported modafinil use was associated with higher numbers of perceived benefits whilst reported frequency of use was not associated with the number of perceived risks. There was also a tentative link between the reported use of modafinil and the reported presence of psychiatric disorders, largely depression and anxiety. Respondents who had reported a psychiatric diagnosis declared higher subjective benefits of modafinil. This may suggest further beneficial effects of modafinil or it may reflect insufficient medical treatment for psychiatric disorders in some people. Overall, the findings of the current study should be beneficial in informing clinicians and legislative bodies about the modafinil user profile and how modafinil is perceived.

Highlights

  • Cognitive enhancing drugs (CEDs) are believed to improve cognitive functions such as attention and motivation [1,2]

  • The findings of the current study should be beneficial in informing clinicians and legislative bodies about the modafinil user profile and how modafinil is perceived

  • They are prescribed for conditions such as dementia, attention deficit hyperactivity disorder (ADHD) and narcolepsy [3, 1]

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Summary

Introduction

Cognitive enhancing drugs (CEDs) are believed to improve cognitive functions such as attention and motivation [1,2] They are prescribed for conditions such as dementia, attention deficit hyperactivity disorder (ADHD) and narcolepsy [3, 1]. The reasons for taking CEDs have been found to include the fear of academic failure, the need to meet high work demands, overcoming procrastination and boosting motivation [11, 12]. Beyond these reasons, some individuals may be self-medicating to treat undiagnosed attention deficit problems that they are experiencing [6, 12]. Given that modafinil is recognised as the most commonly used CED off-prescription [16,17,18], the research reported in the current paper focused on understanding the user profile and perceived effects of modafinil when taken for non-medicinal purposes

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