Abstract
University of Wisconsin solution has been known as the standard solution for liver graft preservation. Alternative preservation solutions have been used in liver transplantation, such as histidine-tryptophan-ketoglutarate (HTK, CustodiolTM) and Celsior solution. Institut Georges Lopez-1 (IGL-1) is a new preservation solution with lower potassium and lower viscosity than UW solution that has recently been used in liver transplant. Data was collected from 100 consecutive liver transplants performed from January 2012 through December 2013 at Hospital Santa Isabel, Blumenau, Brazil. Liver grafts were preserved with IGL-1 solution. All patients were adults and received whole grafts from brain death donors. The mean donor age was 38.0±16.3 years. Cold ischemia time was 361±151 minutes. The mean recipient age was 52.3±11.6 years. The MELD score was 19.19±8.87. First day post-transplant liver enzymes, ALT and AST, levels were 593.5±66 U/L and 665.5±64.2 U/L. None patient presented primary non-function (PNF). In our study, IGL-1 has been shown to be a safe alternative as preservation solution for liver transplantation.
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