The Objective Assessment of dry Nose.

Abstract

Dry nose (DN) is a common symptom in both patients with rhinitis and healthy individuals; however, it is often overlooked. This study aimed to investigate the characteristics of and propose objective diagnostic criteria for DN. This study was conducted from December, 2018 to October, 2021. Patients with complaints of a dry nasal cavity and normal controls were recruited consecutively from the allergy-rhinology outpatient clinic of Beijing TongRen Hospital. Questionnaires were completed by each participant during recruitment to record demographic data. DN test strips were used to evaluate the severity of DN. The length of the strip was recorded at 30 s, 1 min, 2 min, 3 min, 4 min, and 5 min, respectively. Nasal secretions were collected on sponges and allergic status was assessed based on serum sage levels. Twenty (13 men and 7 women) patients with DN and 100 (47 men and 53 women) controls were recruited for the study. The participants' ages ranged from 23 to 73 years (mean = 47.7 years). Nine of the 20 DN patients were diagnosed with vasomotor rhinitis. The weight of the sponges of DN patients was significantly lower than that of controls. At the last time point (5 min), the strips in the control group were significantly longer than those in the DN group. The reference range of 30 s, 1 min, 2 min, 3 min, 4 min, and 5 min of controls was 3.0 mm, 6.0 mm, 10.9 mm, 13.2 mm, 16.8 mm, and 17.0 mm, respectively. Our study indicated that the strip length less than 17.0 mm at 5 min is a valuable reference for the diagnostic of DN in Beijing.