The OA trial bank: individual patient data meta-analysis of trials investigating the effectiveness of intra-articular corticosteroid injections in patients with knee or hip OA

Abstract

s / Osteoarthritis and Cartilage 21 (2013) S63–S312 S259 activities as putting on their clothes. In addition, individuals with multiple co-morbidities had even more complex and challenging selfmanagement experiences, which resulted in family and friends taking on additional “work” to compensate. The multi-joint nature of OA and other co-morbidities further complicated self-management. Many participants described experiencing pain or stiffness in multiple joints at the same time as a result of OA. Additionally, several participants had other health conditions that affected their ability to participate in selfmanagement activities. Conclusions: These findings suggest that previous research on OA selfmanagement overlooks the everyday modifications patients already make to manage their disease prior to surgery, and additionally focuses solely on the individual patient, ignoring the social context of their lives. We found that self-management is not an individual activity but rather can involve the individual's spouse, children, friends and/or co-workers. Further, self-management is complicated by the multi-joint nature of OA and by comorbidities. Future approaches to self-management in OA need to consider these additional issues/aspects as well as the various psychosocial factors that may influence patients’ experiences. 498 THE OA TRIAL BANK: INDIVIDUAL PATIENT DATA META-ANALYSIS OF TRIALS INVESTIGATING THE EFFECTIVENESS OF INTRA-ARTICULAR CORTICOSTEROID INJECTIONS IN PATIENTS WITH KNEE OR HIP OA M. van Middelkoop y, K. Dziedzic z, M. Doherty x, W. Zhang x, J. Bijlsma k, T. McAlindon {, S. Lohmander , S.M. BiermaZeinstra y. y Erasmus MC Med. Univ., Rotterdam, The Netherlands; z Primary Care Sci. Keele Univ., Keele, United Kingdom; xUniv. of Nottingham, Nottingham, United Kingdom; kUniv. Med. Ctr. Utrecht, Utrecht, The Netherlands; { Tufts Univ., Boston, MA; # Lund Univ., Lund,