Abstract

NUMEROUS investigators have found that rapidly growing tissues have a high content of nucleic acids and the relationship of these acids to the synthesis of cellular proteins has been discussed in recent reviews (Caspersson, 1947; Thorell, 1947; and Davidson, 1949). In the light of these results the rapid growth of tissues which are stimulated by hormones presumably would also show an increase in nucleoprotein and nucleic acids. The growth of these tissues is often associated with an increase in the activity of enzymes which in turn can be correlated with functional changes that accompany the growth. Thus there is an increase in succinic and malic dehydrogenases during the growth of hormonallystimulated tissues such as the corpus luteum of the rat during pregnancy (Meyer, Soukop, McShan and Biddulph, 1947; McShan, Erway and Meyer, 1948), and the growth of the prostate and seminal vesicle of the rat under the influence of androgen (Davis, Meyer and McShan, 1949).

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