Abstract

The ultrasonic cardiac output monitor (USCOM) is a noninvasive transcutaneous continuous wave Doppler method for assessing hemodynamics. There are no published reference ranges for normal values in adults (aged 18–60 years) for this device. This study aimed to (1) measure cardiovascular indices using USCOM in healthy adults aged 18–60 years; (2) combine these data with those for healthy children (aged 0–12), adolescents (aged 12–18), and the elderly (aged over 60) from our previously published studies in order to present normal ranges for all ages, and (3) establish normal ranges of USCOM‐derived variables according to both weight and age. This was a population‐based cross‐sectional observational study of healthy Chinese subjects aged 0.5–89 years in Hong Kong. USCOM scans were performed on all subjects, to produce measurements including stroke volume, cardiac output, and systemic vascular resistance. Data from previously published studies (children, adolescents, and the elderly) were included. Normal ranges were defined as lying between the 2.5th and 97.5th percentiles. A total of 2218 subjects were studied (mean age = 16.4, range = 0.5–89; 52% male). From previous studies, 1197 children (aged 0–12, 55% male), 590 adolescents (aged 12–18, 49% male), and 77 elderly (aged 60–89, 55% male) were included. New data were collected from 354 adults aged 18–60 (47% male). Normal ranges are presented according to age and weight. We present comprehensive normal ranges for hemodynamic parameters obtained with USCOM in healthy subjects of all ages from infancy to the elderly.

Highlights

  • The ultrasonic cardiac output monitor (USCOM1A; USCOM Pty Ltd., Coffs Harbour, NSW, Australia) provides a rapid noninvasive measure of hemodynamic parameters using continuous wave Doppler ultrasound (CW Doppler) (USCOM Ltd., 2006a,b).There is increasing interest in measuring flow-based hemodynamic parameters such as cardiac output, (CO), cardiac index (CI), stroke volume (SV), systemic vascular resistance (SVR), oxygen delivery (DO2), and oxygen consumption (VO2) as these are considered to be basic physiological parameters in health, and indicators of illness, where they have been shown to be more a 2017 The Authors

  • Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society

  • The emergence of noninvasive devices has opened the door for measuring hemodynamics in many research and clinical settings

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Summary

Introduction

The ultrasonic cardiac output monitor (USCOM1A; USCOM Pty Ltd., Coffs Harbour, NSW, Australia) provides a rapid noninvasive measure of hemodynamic parameters using continuous wave Doppler ultrasound (CW Doppler) (USCOM Ltd., 2006a,b).There is increasing interest in measuring flow-based hemodynamic parameters such as cardiac output, (CO), cardiac index (CI), stroke volume (SV), systemic vascular resistance (SVR), oxygen delivery (DO2), and oxygen consumption (VO2) as these are considered to be basic physiological parameters in health, and indicators of illness, where they have been shown to be more a 2017 The Authors. The ultrasonic cardiac output monitor (USCOM1A; USCOM Pty Ltd., Coffs Harbour, NSW, Australia) provides a rapid noninvasive measure of hemodynamic parameters using continuous wave Doppler ultrasound (CW Doppler) (USCOM Ltd., 2006a,b). Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society. The emergence of noninvasive devices has opened the door for measuring hemodynamics in many research and clinical settings. Since its introduction in 2001, the USCOM has been used in a wide range of clinical settings, including critical care, anesthesiology, emergency medicine, obstetrics, and neonatology. There is widespread support for the use of Doppler-based ultrasound methods to assess hemodynamics for fluid management in resuscitation and perioperatively (Brierley et al 2009; Thiel et al 2009; Kuper et al 2011; NHS Technology Adoption Centre 2013)

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