Abstract
Measures to define treatment response, such as no evidence of disease activity (NEDA), are routinely used in multiple sclerosis (MS) clinical practice. Although spinal cord involvement in MS is frequent and strongly correlated with future disability accrual, its magnetic resonance imaging (MRI) monitoring, in the absence of spinal cord symptoms, is not routinely performed. This study aimed to assess the impact of spinal cord imaging and specifically, the impact of missing asymptomatic spinal cord lesions, in the definition of NEDA status in a cohort of MS patients treated with disease-modifying therapies (DMTs).
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