Abstract
PROFILEWith assets of $17.1 billion and $13.5 billion, respectively, the Bill and Melinda Gates Foundation and the David and Lucile Packard Foundation are number one and two on the U.S. foundation totem pole. Both are putting a substantial portion of their largess into science, but with a marked difference in focus. Gates, at least in its early days, is largely backing health-related projects, while Packard's science spending tends to be spread more broadly.
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