Abstract

The differential linear sweep voltammetry technique is used to investigate the effect of blood components (erythrocytes, leukocytes, plasma, lymphocyte fraction) on active intermediates of an oxygen reduction ( ·OH, H 2O 2). Lymphocytes are shown to be most effective in the inhibition of radical intermediates of an oxygen reduction. The distinctions in the antiradical activity are found between intact lymphocytes of healthy mice and transformed lymphocytes of ascitic tumor (lymphoblastes). These distinctions depend on cell concentrations and are clearly observed at 2×10 4 ml −1 or higher concentrations of lymphocytes in a chamber. The established peculiarities of the blood components' influence on oxygen intermediates can be used to elucidate the involvement of the blood components into antioxidative protection mechanisms.

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