The new age of medical management of pediatric noninfectious uveitis

Abstract

Pediatric noninfectious uveitis is one of the most challenging conditions ophthalmologists must treat. The myriad of medications now available can make selection of the appropriate treatment regimen daunting but can improve the ultimate outcome. The target audience will be pediatric and comprehensive ophthalmologists. Successful medical management of pediatric non-infectious uveitis depends on the appropriate medication selection and duration of treatment. Corticosteroids, anti-metabolites and biologic agents are among the choices available. Ophthalmologists must be aware of possible adverse effects of individual agents. Steroid-sparing agents, including antimetabolites and biologics, can reduce the complications associated with long term steroid use when treating pediatric non-infectious uveitis. Ophthalmologists may reduce the risk of permanent vision loss and sequelae from uncontrolled uveitis in their pediatric patients by appropriate medical regimen selection and implementation. Corticosteroids, anti-metabolites and biologic agents will be presented in a didactic review and their application will be illustrated in case presentations. Important aspects of medication selection, duration of treatment and the adverse effects will be discussed. Tips for counseling parents on the risks of individual agents will serve to conclude the workshop. Medications available to treat pediatric non-infectious uveitis will be reviewed. Case presentations will illustrate appropriate medication selection and duration of treatment. The risks and benefits of immunomodulation will be discussed to aid the ophthalmologist in counseling families appropriately.