Abstract

What do the following have in common: the blood—brain barrier, glial cells, and the brain interstitium? The answer is that they all affect the environment of nerve cells—the subject of a recent workshop organised by H. F. Cserr and held at the Mt Desert Island Marine Laboratory (MDIBL), Maine, USA. This laboratory has a long tradition of studies in comparative physiology and the control of the fluid environment of the body dating back to the work of E. K. Marshall and Homer Smith, and continuing with currently flourishing work on epithelial transport. While Homer Smith emphasized the advantages to be gained by homeostasis of the blood, the meeting concentrated on the higher order homeostasis required within the brain.

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