Abstract

 Humans are highly social creatures that form intricate relationships, which makes studying social attachment an important part of behavioral neuroscience. These social relationships can reinforce positive well-being, but also inflict psychological damage when broken. Monogamous species form pair bonds, which are uncommon in the predominantly polygamous mammalian kingdom. Using the prairie vole (Microtus orchogaster), an extensively studied model organism, this review will focus on the role of oxytocin (OT) in both regulating and manipulating systems important for these bonds and discuss the possible consequences of changes to these systems. Because of the nature of these bonds, and how OT regulates the associated neural circuits, this research has important therapeutic value.
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