The neural mechanisms underlying the modulation of attentional deployment on emotional stability.

Abstract

Emotional stability, the change of emotion response among situations, was associated with mental illness, such as depression. The current study aimed to explore the modulation of attentional deployment on emotional stability by combining functional magnetic resonance imaging (fMRI) and a sequential risk-taking task. During the task, participants were asked to open a series of boxes consecutively and decided when to stop. Each box contained a reward, except one containing a devil to zero reward in the trial. When participants stopped, both collected gains and missed chances were revealed. The attentional deployment was manipulated during the outcome feedback, i.e., inducing participants to focus on the good part (GF context) or the bad part (MF context) of the decision outcome. Besides, the Control context was also set, in which the attentional deployment was not manipulated. The behavioral results showed that the emotional stability was stronger in GF context relative to MF and Control contexts. At the neural level, with outcomes getting better, activations of ventral striatum (VS) and superior frontal gyrus (SFG) increased faster in GF context than that in MF and Control contexts. In addition, in GF context, the changing of SFG activation with outcomes getting better was associated with emotional stability. The current study highlighted that focusing on the good part of decision outcomes could enhance emotional stability effectively and SFG played a vital role in this process.