The neural mechanisms underlying directional and apparent circular motion assessed with repetitive transcranial magnetic stimulation (rTMS)

Abstract

Dynamic Glass patterns (GPs) are a class of visual stimuli that evoke apparent motion and are commonly used to investigate the interaction between global form and motion processing in the visual system. Neuroimaging studies showed that (complex) circular dynamic GPs mainly activate areas along both the ventral and the dorsal stream such as hMT+, V3b/KO, dorsal V4 and LOC, whereas directional motion from rotating random dot kinematograms (RDKs) mainly activates the human MT complex (hMT+) and area V6. However, despite the large number of correlational information from fMRI studies, there is scarce evidence about the causal involvement of these brain areas in the perception of dynamic circular GPs and rotating RDKs. The aim of this study is to compare the neural basis of dynamic circular GPs and rotating RDKs by temporarily interfering with repetitive transcranial magnetic stimulation (rTMS) delivered over two visual areas largely involved in form and motion processing, such as V1/V2 and hMT+. Our results showed that rTMS over hMT + interfered only with the processing of rotating RDKs but not with the processing of circular dynamic GPs. On the other hand, rTMS delivered over early visual areas (V1/V2) did not interfere with the processing of both visual stimuli. These results suggest that partially different neural substrates subtend the processing of circular directional motion and apparent non-directional motion.