Abstract
Background: Globally, arterial hypertension (AH) has increased by 90% over the last four decades, and has increased by 1.6% in Peru over the previous four years. Scientific evidence indicates the prevalence of depressive symptoms in patients with AH and its importance in the comprehensive evaluation of the adult for adherence to clinical treatment. Previous studies carried out in the Peruvian population with AH mostly report the prevalence and associations, but do not indicate which depressive symptoms are more relevant in patients with AH. This study involved a network analysis of depressive symptomatology in Peruvian patients with AH using network estimation. Network analysis is used in this study for analysis, control, and monitoring purposes. Method: A representative cross-sectional study at the national level, using secondary data from 2019 Demographic and Family Health Survey (ENDES) was performed. The sample used included men and women of age over 17 years diagnosed with AH and was able to respond to Patient Health Questionnaire-9 (PHQ-9). Results: The symptoms of depressive mood (bridging force and centrality) and energy fatigue or loss (bridge centrality) play an essential role in the network structure, as does the feeling of uselessness in terms of closeness and intermediation. Conclusion: The study highlighted the symptoms related to depressive mood and energy fatigue or loss as bridging symptoms, which could trigger a depressive episode in patients diagnosed with AH. The results will contribute to developing personalized treatments aimed at patients with specific depressive symptoms who have also been diagnosed with AH. The study analysis presents statistical coefficients of effect size (≤ 0,1 = small; > 0,1 to < 0,5 = moderate; ≥ 0,5 = large) to determine network connections.
Highlights
This shows that people with arterial hypertension have a higher level of “Depressed mood”
This research aimed to explore the dynamics of depression symptoms in adults having Pulmonary arterial hypertension (PAH)
In conclusion, the most central reagents in the network (2 and 4) with the most connections report a moderate relationship and are relatively close to the system. These network findings suggest possible routes of greater concentration and dynamism in the process of depressive symptomatology that at a higher level and prevalence, it is more likely to activate the interactive development of the various symptoms of Patient Health Questionnaire-9 (PHQ-9), which may even lead to a depressive episode
Summary
1. The authors need to describe how common is depression among people with a diagnosis of arterial hypertension . 2. The appropriate abbreviation for Arterial Hypertension would be AHT or AH. The appropriate abbreviation for Arterial Hypertension would be AHT or AH Previous studies carried out in the Peruvian population with AH mostly report the prevalence and associations, but do not indicate which depressive symptoms are more relevant in patients with AH. Conclusion: The study highlighted the symptoms related to depressive mood and energy fatigue or loss as bridging symptoms, which could trigger a depressive episode in patients diagnosed with AH. The salience of depression as a comorbidity among people with arterial hypertension needs to be highlighted.
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