The Neoplastic Whorls-Soft Tissue Perineurioma

Anubha Bajaj,Jun Wan

doi:10.14302/issn.2689-5773.jcdp-20-3292

Abstract

Perineurioma is an exceptional, benign neoplasm entirely composed of neoplastic perineurial cells and arises from the peripheral nerve. Pertaining to location, the neoplasm predominantly demonstrates configurations such as intra-neural or extra-neural, confined to the soft tissue. Perineurioma was initially scripted by Lazarus and Trombetta in 1978 and is additionally nomenclated as localized hypertrophic neuropathy1. Extra-neural soft tissue perineurioma and mucosal (intestinal) perineurioma are frequent, in contrast to intra-neural perineurioma or localized hypertrophic neuropathy subtype1, 2.

Highlights

Perineurioma is an exceptional, benign neoplasm entirely composed of neoplastic perineurial cells and arises from the peripheral nerve
Low-grade fibromyxoid sarcoma and intramuscular / cellular myxoma are neoplasms which demonstrate distinct, identical features such as a) occurrence in middle aged adults with a preponderance of lesions upon the extremities b) on cytological examination, aforesaid neoplasia enunciate bland, uniform spindle-shaped cells admixed within a myxoid stroma c) aforementioned neoplasia depict overlapping immune phenotypes[1,2]
Extra-neural perineurioma is commonly delineated within superficial soft tissue of trunk and extremities, especially the hands[5,6]. It is a variant of extra-neural soft tissue perineurioma and is composed of plump, spindle shaped and epitheloid tumour cells encompassed in a hyalinised stroma

Summary

Introduction

Perineurioma is an exceptional, benign neoplasm entirely composed of neoplastic perineurial cells and arises from the peripheral nerve. Low-grade fibromyxoid sarcoma and intramuscular / cellular myxoma are neoplasms which demonstrate distinct, identical features such as a) occurrence in middle aged adults with a preponderance of lesions upon the extremities b) on cytological examination, aforesaid neoplasia enunciate bland, uniform spindle-shaped cells admixed within a myxoid stroma c) aforementioned neoplasia depict overlapping immune phenotypes[1,2].

Results

Conclusion