Abstract
Neonatal infections occur in a range of different clinical circumstances. An infection in a premature infant already several weeks into the course of intensive care is likely to be very different from an infection in the first few hours of life in a term baby. The appropriate response is different for each situation. Bacterial infections may be considered to be congenital or nosocomial. Babies may acquire infection while in the uterus, particularly if the membranes have ruptured and amnionitis has become established, in the birth canal or during very early postnatal life. The common pathogens in the U K are group B streptococcus and gram negative organisms. Neonates receiving intensive care are at high risk of developing nosocomial infections. These infections are often due to low grade pathogens such as the coagulase negative staphylococcus (CONS) or, less frequently, invasive fungal infections.
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