Abstract

The major arboviral diseases in mainland China include Japanese encephalitis, dengue fever, Crimean-Congo hemorrhagic fever (also known as Xinjiang hemorrhagic fever), and tick-borne encephalitis. These and other newly found arbovirus infections due to Banna virus and Tahyna virus contribute to a large and relatively neglected disease burden in China. Here we briefly review the literature regarding these arboviral infections in mainland China with emphasis on their epidemiology, primary vectors, phylogenetic associations, and the prevention programs associated with these agents in China.

Highlights

  • Arboviruses are maintained in nature in cycles involving hematophagous arthropod vectors and susceptible vertebrate hosts [1]

  • More than 550 arboviruses have been identified, among which are more than 130 virus species that can cause disease in susceptible vertebrate hosts [2]

  • We summarize relevant information available in the Chinese scientific literature, highlight the current situation of arboviral infections in mainland China, and describe current practices and recommendations regarding surveillance and prevention measures

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Summary

Introduction

Arboviruses (arthropod-borne viruses) are maintained in nature in cycles involving hematophagous arthropod vectors and susceptible vertebrate hosts [1]. Japanese encephalitis virus (JEV), dengue virus (DENV), Crimean-Congo hemorrhagic fever virus (CCHFV) ( known as Xinjiang hemorrhagic fever virus, XHFV), and tick-borne encephalitis virus (TBEV) are the four principal arboviruses of public health importance in mainland China at present [3]. JE prevalence has been high in China, where major outbreaks occurred in 1966 and 1971 with reported disease incidence of .15/100,000 and 20.92/100,000, respectively [10].

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