Abstract
OPINION article Front. Integr. Neurosci., 06 June 2011 https://doi.org/10.3389/fnint.2011.00022
Highlights
A further difficulty in defining the specific clinical picture for the patient is that tics may change during the course of illness and new tics can issue (Du, 2010; Liao, 2010; Worbe, 2010)
The development of diagnostic instruments that try to bypass the timing of the different clinical manifestations, such as the Diagnostic Confidence Index (Robertson, 1999), demonstrate the need for a sound description of such an ever-changing clinical picture
Considering that a significant percentage of these patients may show a certain degree of improvement up to a complete disappearance of all clinical manifestations by the major age, deep brain stimulation (DBS) has classically been indicated for those patients failing to show a significant amelioration of symptoms during adulthood (Mink, 2006)
Summary
A further difficulty in defining the specific clinical picture for the patient is that tics may change during the course of illness and new tics can issue (Du, 2010; Liao, 2010; Worbe, 2010). OCD is documented in up to 50% of patients in published experiences in Literature (Freeman, 2000; Robertson, 2000), while in our experience obsessive traits of personality can be demonstrated in up to 85% of patients.
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