Abstract
Struvite stones represent the most common cause of the rapidly growing staghorn calculi whose predisposing factors include female sex, stasis from urinary tract malformations or obstruction, neurogenic bladder, among others. Their relevant morbidity is ascribed to the frequent association with recurrent urinary tract infections (UTI), pyelonephritis, perinephric abscess or even sepsis, not to mention the potential loss of renal function. Moreover, lower social economic status and poor health care quality are closely related to reduced access to procedures for stone [...]
Highlights
The authors found a similar frequency of metabolic abnormalities in 24-hour urine tests between groups, but only important for hypocitraturia
There was no significant difference in new events between groups, and treatment of metabolic abnormalities among patients with MAP stones rendered them prone to the same risk for a new event as those without any metabolic disturbance
Iqbal et al[1], for instance, reported much higher rates of hypercalciuria (43%) and lower rates of hypocitraturia (14%) among pure struvite stone formers than the ones presented by Danilovic et al[4]
Summary
The authors found a similar frequency of metabolic abnormalities in 24-hour urine tests between groups, but only important for hypocitraturia. There was no significant difference in new events between groups, and treatment of metabolic abnormalities among patients with MAP stones rendered them prone to the same risk for a new event as those without any metabolic disturbance. Metabolic abnormalities in pure struvite stone formers appear to be more common than previously reported, the profile of metabolic alterations differ among reports.
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