The natural soluble form of IL-18 receptor β exacerbates collagen-induced arthritis via modulation of T-cell immune responses

S Veenbergen,L A B Joosten,F A J Van De Loo,O J Arntz,M B Bennink,R L Smeets,W B Van Den Berg

doi:10.1136/ard.2008.100867

The natural soluble form of IL-18 receptor β exacerbates collagen-induced arthritis via modulation of T-cell immune responses

S Veenbergen, L A B Joosten + Show 5 more

https://doi.org/10.1136/ard.2008.100867

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Journal: Annals of the Rheumatic Diseases	Publication Date: Feb 2, 2009
Citations: 52

Affiliation: Radboud University Nijmegen, Radboud University Nijmegen Medical Centre

#IL-17 Production #Splenic Antigen-presenting Cells + Show 8 more

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Abstract

Objective:IL-18 is a pluripotent cytokine that has been implicated in the development of rheumatoid arthritis. A soluble form of the IL-18 receptor accessory protein (sIL-18Rβ) with unknown function has recently...

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