Abstract

We are entering an era of unprecedented opportunities and challenges in health and medicine. With recent advances in science and technology, as well as the advent of big data, we have seen tremendous developments in biomedical science and the practice of medicine. Yet, the global disease burden continues to rise, demand for care is increasing, costs are unsustainable, and health inequity persists. Globally, cardiovascular disease (CVD) is the No. 1 disease burden, driven by the rise in noncommunicable diseases such as obesity and diabetes mellitus. The need for cardiovascular medicine will continue to grow as the global population ages and developing countries become more affluent, adopt a Western lifestyle, and become more urbanized. There have been impressive advances in cardiovascular diagnostics and therapeutics in the areas of precision medicine, molecular/metabolic imaging, endovascular procedures, gene and cell therapies, RNA therapeutics, tissue engineering and regenerative medicine, and digital health. However, cardiovascular care is fragmented and expensive. Furthermore, in the current healthcare landscape, access, quality, and costs are top priorities. The Affordable Care Act introduced a number of payment and delivery system reforms to increase the quality of health care while controlling costs, such as accountable care organizations, patient-centered medical homes, and mechanisms to link payments to quality. This value-focused health care is here to stay; therefore, we must adopt this approach for cardiovascular medicine. Importantly, we must do more to move from a disease-treatment model to a model that prioritizes and enables prevention. Unfortunately, current health challenges do not always lend themselves to straightforward solutions. There is a real need for evidence-based, independent, and nonpolitical advice that can inform health policy and thereby shape solutions and drive change. Indeed, society can benefit enormously from the activities of an independent scientific academy with the directive to mobilize the best minds to provide objective …

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