Abstract
The Prune Belly Syndrome or Triad Syndrome is a rare disorder characterized by hypoplasia or aplasia of abdominal musculature, urogenital anomalies and undescended testicles. The majority of the reported cases are males. A female case of the mild variant of this syndrome is presented. The light and electron microscopic changes in the voluntary muscles are described. They consisted of variations in fibre size, fibre necrosis, an increase in sarcolemmal nuclei, the presence of capillaries within muscle fibres, excessive collagen accumulation, Z-line abnormalities, sarcoplasmic reticulum dilatation and myofilamentous disarray and loss. We propose the hypothesis that a genetically-determined or congenital type of myopathy may be the basis of this syndrome.
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