Abstract
1. 1. One of every five anterior descending coronary arteries (human) runs for all or part of its course in the myocardium. 2. 2. Such mural arteries have a considerably thinner intima than corresponding epicardial branches, and the extremes of medial hypertrophy and atrophy are found less frequently in them. 3. 3. Atheroma occurs only rarely in these mural stretches. 4. 4. These differences in the normal and morbid anatomy seem to be related to a medialike protective action of the surrounding myocardium. 5. 5. The mural coronary artery provides one further example of the paramount importance of local factors in the genesis of atheroma.
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