Abstract

1 Introduction 2 The Innate Mucosal Defense System 3 The Mucosal Epithelium Bridges Innate with Acquired Mucosal Immunity 4 An IEL–IEC Intranet 5 Inductive and Effector Lymphoepithelial Sites of the Mucosal Immune System 6 Mucosal T Cells and Cytokines 7 Induction of Mucosal Immunity and Vaccines 8 Mucosally-Induced Tolerance 9 Conclusions 10 Acknowledgments Keywords: mucosal immune response; innate mucosal defense system; mucosal epithelium bridging innate with acquired mucosal immunity; IEL and IEC crosstalk at intestinal mucosal barrier; mucosal immune system inductive and effector lymphoepithelial sites; cytokine and chemokine responses to mucosal pathogens; mucosally-induced tolerance; mucosal immunity and vaccine induction

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