Abstract

The Movement Disorder Society (MDS) Criteria for the Diagnosis of Multiple System Atrophy (MSA) is a new diagnostic criteria which aimed to improve the accuracy of diagnosis in the early stages of the disease, leading to improved patient enrollment in clinical trials. The criteria is characterized by four levels of diagnostic certainty: neuropathologically established MSA, clinically established MSA, clinically probable MSA, and possible prodromal MSA. This article describes the differences between the new diagnostic criteria and the second consensus statement on the diagnosis of multiple system atrophy, and also provides some points to consider when using the new criteria in daily practice.

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