Abstract
Somatic cell variation is a broad term that covers heritable changes in phenotype due to mutational or epigenetic changes (Siminovitch, 1976). Mutational changes represent alterations in the primary structure of the DNA sequence and range from events as small as base-pair substitutions to those as large as loss of entire chromosomes. In contrast, epigenetic changes do not affect the primary structure of the DNA sequence, which makes them somewhat more difficult to analyze.
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