Abstract
Glioblastoma is the most devastating form of glial tumor. To tackle how the interplay between intra-tumoral heterogeneity and diffuse infiltration drives tumor invasion, we surveyed the methodologies predominantly employed to dissect glioblastoma migration in vitro. Here, we propose tumor-sphere spreading on a laminin grid micropattern as a biomimetic mimicry of (1) the gradual diffusion in the brain and (2) the motility modes observed along Scherer's structures. Through a set of semi-automated tools, we assessed the glioblastoma motility landscape from a set of human glioblastoma propagating cells (hGPCs).
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
