Abstract

The need for blood is essential, but there is no timely access to safe blood for millions of individuals who need a transfusion. Additionally, blood transfusions can also be the fastest and simplest form of checking for the existence of transfusion-transmitted diseases to the recipients. Blood safety concerns are an issue of great concern in Middle Eastern Countries in which the inaccessibility or provision of unsafe blood has an adverse effect on morbidity and mortality in the region. Additionally, many organizations and safety procedures of blood transfusion in this region need to be updated. Articles containing the key phrases Middle Eastern Countries, Blood, blood donor, blood transfusion, transfusion safety, transfusion-transmitted infections, and transfusion guidelines published from 2003 to 2020 in MEDLINE, PubMed, Scopus, and Google Scholar. Therefore, to determine the most prevalent causes of transfusion-transmitted disease among blood donors in the Middle East countries, this literature review was intended for research.
 Based on the data gathered were potentially related to HBsAg and HCV prevalence in blood donors from most of the middle eastern countries. While no positive cases of either HIV Ag-Ab or syphilis antibodies have been recorded especially among the blood donated from Egypt and Saudi Arabia. Based on recent studies findings, WHO, and the Food and Drug administration transfusion transmission of SARS-CoV-2 to recipients did not occur via blood transfusion. So that, In Middle Eastern countries, transfusion-transmitted infection remains a formidable problem. A similarly wide constellation of economic and operational challenges in the area parallels the diverse array of pathogens; this calls for a systemic solution that, as proposed by the WHO, involves regulatory, structural, and training initiatives.

Highlights

  • Blood donation is recognized as an effective lifesaving procedure in medicine and, most prominently, in medical emergencies [1]

  • Blood safety concerns are an issue of great concern in Middle Eastern Countries in which the inaccessibility or provision of unsafe blood has an adverse effect on morbidity and mortality in the region

  • To determine the most prevalent causes of transfusion-transmitted disease among blood donors in the Middle East countries, this literature review was intended for research

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Summary

INTRODUCTION

Blood donation is recognized as an effective lifesaving procedure in medicine and, most prominently, in medical emergencies [1]. Public health often faces challenges of blood safety due to transfusion- transmissible infections (TTI). This has become higher, especially within risk groups such as children and pregnant women with Malaria, hemorrhage, or pregnancy anemia [2]. Only 47% of blood donors were screened [4]. At least 13 million donors were deferred because of TTI infection that could be spread by blood, including HIV, HBV, HCV and syphilis, a pre-existing medical condition or anemia [3]. To determine the most prevalent causes of transfusion-transmitted disease among blood donors in the Middle East countries, this literature review was intended for research

STUDY DESIGN
Blood Donation and Blood Safety in the Middle East Countries
Hepatitis virus
Screening Methods
Bacteria contamination
Syphilis
Malaria and Protozoa
Specific Agents of Recent Concern
Dengue virus
CONCLUSION
Findings
LIMITATION
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