The Morphology of the Brain Neurons: Box-Counting Method in Quantitative Analysis of 2D Image

Abstract

This chapter calls attention to the difference among basic terms of fractal geometry and fractal analysis presented on 2D images of neurons from the human dentate nuclei. In further quantitative estimation, the most popular technique of fractal analysis, i.e., the “box-counting method,” was used. Image preprocessing was investigated, precisely how images at different sizes, resolutions, and rotation angles could influence in the magnitude of the box dimension. All preprocessing tasks were evaluated on 17 standardized images from the dentate nuclei, classified into three groups due to their width and height.