The monitoring of cadmium, zinc and copper in the kidneys and liver of humans deceased in the region of Cracow (Poland)

Abstract

Cadmium, zinc and copper levels were determined in the renal cortex and liver of 60 inhabitants of Cracow, Poland. Cadmium levels in the renal cortex were contained in broad limits of 5-176 μg/g, mean 50.6 μg/g (wet weight). Maximum levels were found in the age group of about 50-60 years. The levels were slightly higher in men (53 μg/g) than in women (45 μg/g), with no effect of location within the region. The levels in smokers (62 μg/g) were much higher than in non-smokers (32 μg/g). The above relations were less pronounced for cadmium levels in the liver. Whole body retention of cadmium followed the pattern of cadmium in renal cortex. The level of zinc in renal cortex reflected those of cadmium. A significant proportion of the population (54% in smokers, 9% in non-smokers) showed cadmium levels in renal cortex exceeding the reference level of 50 μg/g recently accepted for general population. In the view of the authors the exposure to cadmium of the population of Cracow is excessive and calls for attention.