Abstract
Evidence for immunoadjuvant activity of the Helianthus tuberosus L. polysaccharide was obtained in an antibody-producing cell model. Dectin-1 and TLR-6 were identified as major receptors required for biological activity of polysaccharide in a TNF-α stimulation model. The CR3 receptor was not implicated in polysaccharide recognition in the same model. Enzyme treatment of the H. tuberosus L. polysaccharide demonstrated the presence of s-(1 → 4) and s-(1 → 3) glycosidic bonds.
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