Abstract
The article highlighted the problem of meat cattle genetic defects. The aim was the development of DNA tests for some genetic defects diagnostics, the determination of the animal carriers and their frequencies tracking in time. The 1490 DNA samples from the Aberdeen Angus (n = 701), Hereford (n = 385), Simmental (n = 286) and Belgian Blue (n = 118) cattle have been genotyped on the genetic defects by newly created and earlier developed DNA tests based on AS-PCR and PCR-RFLP methods. The Aberdeen Angus cattle genotyping has revealed 2.38 ± 0.31% AMC-cows and 1.67 ± 0.19 % AMC-bulls, 0.65 ± 0.07% DDC-cows and 0.90 ± 0.10% DDC-bulls. The single animals among the Hereford cattle were carriers of MSUD and CWH (on 0.27 ± 0.05%), ICM and HY (on 0.16 ± 0.03%). The Simmental cattle were free from OS. All Belgian Blue livestock were M1- and 0.84%-CMD1-carriers. The different ages Aberdeen Angus cattle genotyping has shown the tendency of the AMC- and DDC frequencies to increase in the later generations. The statistically significant increase of DDC of 1.17% in the cows’ population born in 2019 compared to those born in 2015 allows concluding the further development of the DNA analysis-based measures preventing the manifestation of the genetic anomalies in meat cattle herds is necessary.
Highlights
The current state of molecular genetics allows for early diagnosis of such animals, and the main task of any genetic laboratory working in the field of beef cattle breeding is to possess fast and accu
The current state of molecular genetics allows for early diagnosis of such animals, and the main task of any genetic laboratory working in the field of beef cattle breeding is to possess fast and accurate diagnostic methods, which must be constantly improved using the latest advances based on the fluorescence detection
Currently most animals affected by type I genetic diseases die soon after birth, and those that survive with the manifestation of non-lethal genetic defects of type II require the costs of care and treatment
Summary
Academic Editors: Bianca Castiglioni and Emilia Bagnicka. Publisher’s Note: MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations. One of the most important strategic objectives is to increase the consumption of meat products, in particular beef, as the main source of essential amino acids. In this regard, the efforts of specialists of the beef cattle industry are constantly directed at finding ways to increase the productivity of animals, and the use for this purpose of breeding material of specialized meat cattle breeds is very promising [1]
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