The modified NUTRIC score as a predictor of 28-day mortality in patients with sepsis

Abstract

Background Malnutrition is prevalent among severely ill individuals hospitalized in ICUs (intensive care units). In order to determine the potential for nutritional consequences in ICU patients, the score of ‘modified nutrition risk in the critically ill’ (mNUTRIC) is applied. This research aimed to determine whether the mNUTRIC score could be employed in septic patients for predicting 28-day death. Methods Four hundred ten individuals hospitalized in the ICU with sepsis were involved in this prospective observational research. To evaluate nutritional status upon hospitalization to the ICU, the mNUTRIC score was applied. Demographic and clinical characteristics were used to determine the mNUTRIC score. Results Four hundred ten individuals with sepsis participated in this investigation. The 56.6% of cases were shown to be at elevated risk of malnutrition (mNUTRIC ≥ 5 points), whereas 43.4% showed a lower risk (mNUTRIC < 5 points). During 28 days of being hospitalized in the ICU, 225 patients (54.9%) died. The mortality rate increased significantly in the group with an mNUTRIC score of greater than or equal to 5 compared with the group with an mNUTRIC score of less than 5 (P < 0.001). Multivariate analysis revealed a link between the mNUTRIC score and 28-day mortality (OR = 1.715, 95% CI = 1.549–1.898). The AUC (area under the curve) for mNUTRIC’s prediction of 28-day mortality was 0.866 (specificity 79.5% and sensitivity 80.9%) with the best cut-off value of 5. Conclusion When evaluating the likelihood of death within 28 days in patients with sepsis, the mNUTRIC score performed well as an independent predictor.