Abstract

The effect of Vibrio cholerae neuraminidase (VCN) on the in vivo growth characteristics of the Landschütz ascites tumour has been studied. A considerable reduction in tumour cell numbers following the transplantation of VCN-treated cells as compared to untreated cells has been shown which is readily reversible by in vitro incubation of the treated cells for a short period prior to transplantation. The possible significance of this is discussed.

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