Abstract
The paper deals with an empirical mathematical model serving for the time evolution of post-operative blood perfusion in burn wounds developed in the setting of surgical treatment of full thickness, or non-healing deep dermal burns involving application of Split Thickness Skin Grafts (STSG), and Autologous Platelet Concentrate (APC), with the main goal of early assessment enhancement and healing prognosis of burns. Numerical parameters of the model including a 95% confidence level prediction interval were determined using the nonlinear fit procedure. We cautiously claim that the suggested model could serve as a beneficial tool in objective comparisons of treatment efficacy and facilitating the decision making process. However, reliably determined model parameters still require a large amount of laser Doppler imaging data to be processed for individual kinds of treatment.
Highlights
Laser Doppler Imaging (LDI) has been entrenched and almost ubiquitous in burns diagnostics since it first became available, one can observe persistent striving for new means of LDI data processing which would be able to contribute additional benefits, improve the result accuracy and reliability, set forward objective comparison of treatment efficiency [1], [2], [3], [4], [5] and facilitate local treatment strategy decision making [6], [7] and [8]
The aforementioned reasons, together with increasing emphasis placed on outcomes following treatment of deep dermal and full
All procedures involved in the study were carried out by the objective measurement of blood perfusion using the laser Doppler imaging technique
Summary
Laser Doppler Imaging (LDI) has been entrenched and almost ubiquitous in burns diagnostics since it first became available, one can observe persistent striving for new means of LDI data processing which would be able to contribute additional benefits, improve the result accuracy and reliability, set forward objective comparison of treatment efficiency [1], [2], [3], [4], [5] and facilitate local treatment strategy decision making [6], [7] and [8]. The aforementioned reasons, together with increasing emphasis placed on outcomes following treatment of deep dermal and full. All patients were fully informed about the study, and gave informed consent to the treatment and the subsequent measurements. The study presented is a non-randomized prospective monocentric data analysis based on objective testing of outcomes of surgery on deep burns. All procedures involved in the study were carried out by the objective measurement of blood perfusion using the laser Doppler imaging technique All procedures involved in the study were carried out by the objective measurement of blood perfusion using the laser Doppler imaging technique (see Ref. [15] and references therein)
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