Abstract
In order to identify the structural and dynamic characteristics of comorbid non-psychotic psychopathological symptoms in patients on the synthetic opioid substitution therapy program, 100 patients of the narcological dispensary were examined with the help of the Simptom Check List – 90 – Revised. The study used the inclusion and exclusion criteria that are identical to the criteria for participation in the substitution therapy program. The results were distributed to 3 levels, which correspond to the degree of clinical significance of the symptoms: - minimal (discomfort for this reason occurs rarely or does not occur at all, it has a low intensity) - the range of results obtained is from 0 to 0.50; - subclinical (the presence of not frequent, moderately intense discomfort for this reason) - the range of values is from 0.51 to 1.50; - clinical (frequent or persistent high intensity discomfort for this reason) - range of values greater than 1.51. The study found that non-psychotic mental disorders among this group of patients have three stages of development. All groups of symptoms are considered in the context of the three main classes of disorders (patho-affective — anxiety and depression symptoms; pseudo-neurotic — obsessive-compulsive phenomena; psycho-vegetative symptoms and self-perception disorders; and psychoorganic — associative disorders, paranoia and hostility) and two groups of intermediate symptoms (phobic — intermediate between pathogenic and pseudoneurotic and psychotic - intermediate between psychoorganic and pseudoneurotic). Also, according to the results of the assessment of the correlation dynamics of symptom groups, a model of psycho-pathogenesis of non-psychotic mental disorders in people who are on the program of drug addiction substitution therapy was constructed
Highlights
Among a wide range of psychopathological aspects of the participation of addicted persons in the programs of synthetic opioids substitution therapy, one of the main issues is the diagnostics of non-psychotic psychopathological which are imitating neurotic spectrum violations [1; 2]
The main thesis is the necessity to differentiate between two groups of psychopathological disorders – neurotic ones, the development of which in persons with opioid addiction is doubtful due to damage to the mechanisms of the implementation of psychogenic factors, and neurosis or pseudoneurotic ones, which is a consequence of organic and personality disorders and is manifested by symptoms that are structurally identical to neurotic [5]
The result of the evaluation of the overall level of psychopathological symptoms according to the severity index of psychopathological symptoms (GSI integrative index) shows the following distribution of study population: the minimum level is 12 (12%) persons, subclinical – 52 (52%) persons, clinical – 36 (36%) persons
Summary
Among a wide range of psychopathological aspects of the participation of addicted persons in the programs of synthetic opioids substitution therapy, one of the main issues is the diagnostics of non-psychotic psychopathological which are imitating neurotic spectrum violations [1; 2]. Opioid addiction is a factor that massively distorts the essential stereotypes of personality response to a stress and distress, both on psychological, psychosocial and behavioral, and in neuro-metabolic levels [6; 7]. This allows us to consider the contingent of persons undergoing the substitution therapy programs as a homogeneous model for studying the mechanisms of the relationship between chemical dependencies and psychopathological disorders of the neurotic or pseudo-neurotic group [8; 9]
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