Abstract
Zaluzanin C, a substance extracted from several species of the genus Zaluzania (Compositae), has been shown to inhibit protein synthesis in intact HeLa cells preferentially to DNA and RNA synthesis. “In vitro” protein synthesis was also blocked by zaluzanin C and the study of the effects of the drug on resolved model systems indicates that it inhibits enzymic translocation of peptidyl-tRNA specifically.
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Schedule a callMore From: Biochemical and biophysical research communications
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