Abstract
Adult mammalian erythroblasts from an anaemic rabbit were separated into fractions of cells at different stages of development using the velocity sedimentation technique. The iron content of the stroma and cytoplasm of the cells in each fraction was determined by atomic absorption spectroscopy. A high proportion of the iron in the dividing erythroblasts was found to be associated with the cell stroma. After the final cell division the proportion of stromal iron rapidly declines and it appears that stromal iron is mobilised at this stage and utilised by the non-dividing erythroblasts for haemoglobin synthesis.
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