Abstract
The aim of investigation to study the of some clinico-microbiological characterisrics of mixed intestinal infections in children of early age. Material and methods – the children under the age of 3 (infants and children), hospitalized in the Children’s Clinical Hospitals № 1 and 7 in Baku for the 2019 year have been examined. Bacteriological and serological studies were carried out to diagnose intestinal infections on the day of admission to hospital feces of sick children were take as material for analyses. Totally the 117 children have been observed. To convirm the diagnosis of bacterial intestinal infection feces were cultured with subsequent detection of sensitivity to antibiotics and for viral intestinal infection, immunochromatografic test was used. The bacteriological and serological investigations were arried out in the Scientific-Research Institute of Medical Prophylaxis named after V. Y. Akhundov during 2019 year. Results – As a result of our studies, 33,3% (39) of children had mixed infection: a combination of viruses, particularly rotaviruses with St.aureus, E.Coli and C.albicans. From observing children 25 were under 6 month (21,4%), 15 – 7-12 month (12,8%), 77 – 1-3 years (65,8%). The combination of rotaviruses with other viruses (adenovirus and astrovrus) were the most frequently observed ones (5,1±2,0% and 6,8±2,3% accordingly) (p=0,167; p=0,067). Among opportunistic microbes the S.albicans was a leader. (In 18 (15,4%) patients). C.albicans was with rotavirus (p=0,063), in 5 (4,3±1,9%) with St.aureus and rotavirus (p=0,118) and in 4 (3,4±1,7%) with rotavirus and E.Coli (p=0,056). The viral intestinal infection with 2 associates occured in 5 (4,3±1,9%) of patients – rotavirus + St.aureus + C.albicans and rotavirus + E.Coli + C.albicans (p=0,056).
Highlights
The problem of mixed bacterial intestinal infections in children of early age attracts special attention, as they are characterized by a severe course 2 high lethality
To confirm the diagnosis of bacterial intestinal infection feces were cultured with subsequent detection of sensitivity to antibiotics and for viral intestinal infections, immunochromatografic test was used
From observing children 25 were under 6 months (21,4%), 15 – 7-12 months (12,8%), 77 – 1-3 years (65,8%)
Summary
The problem of mixed bacterial intestinal infections in children of early age attracts special attention, as they are characterized by a severe course 2 high lethality. Nowadays one to achievements in the study of etiology of acute intestinal infections (Aİİ), discovery of new causative agents and improvement of their diagnostics is still an actual problem of mixed intestinal infections [1,2,3,4]. At the modern stage of development of bacteriological and virological diagnostics, it became possible to detect in one sample of feces 2-3 pathogenic causative agents of intestinal infections, which gives possibility to refer such forms of diseases to mixed types [1,2,3, 6,7,8]. Aİİ occurs in children as mixed infections, caused by virus - viral and viral - bacterial associations, that requires
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