Abstract
The miscibility of mixtures of poly( d, l-lactide-co-glycolide) (PLG) with two amphiphilic molecules was investigated when they were spread at air/water interface. The plateau in the π–A isotherms of the PLG mixture with cationic amphiphile, C 12AzoC 6PyBr, became short with gradually increasing the proportion of the amphiphile and the aggregates appeared in LB film became more uniform, both in scale and in shape, in comparing with the wormlike aggregation of pure PLG, by atomic force microscopy (AFM). However, the π–A isotherm of the PLG mixed with non-ionic amphiphile, C 16AzoPy, showed no obvious changes corresponding to pure polymer except the molecular area increasing in some extent, and the domains with different heights on the LB film were clearly observed. Combing the results of UV–vis spectra, it is concluded that the PLG is basically miscible with C 12AzoC 6PyBr but is not with C 16AzoPy, which is favorable to be a carrier for anionic biomolecules.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Colloids and Surfaces A: Physicochemical and Engineering Aspects
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
