Abstract

Melioidosis is being diagnosed more frequently from Indian subcontinent in the recent days. It is a serious multisystem infection caused by Burkholderi pseudomallei. 1-2 We discuss the case of a 55 year old Diabetic patient, who presented with complaints of fever, cough, breathlessness and loss of weight of one month duration. Due to poor response to conventional treatment, he was further investigated – Bronchoscopy and CT Thorax was done. Bronchial wash and sputum culture confirmed Pulmonary Melioidosis. The patient received treatment with Inj. Ceftazidime and was continued on oral Cotrimoxazole. Treatment was successful with good clinic radiological resolution. The patient is under follow up and is asymptomatic. Keywords: burkholderia, diabetics, melioidosis, pneumonia

Highlights

  • Melioidosis is being diagnosed more frequently from Indian subcontinent in the recent days. It is a serious multisystem infection caused by Burkholderi pseudomallei. 1-2 We discuss the case of a 55 year old Diabetic patient, who presented with complaints of fever, cough, breathlessness and loss of weight of one month duration

  • Melioidosis is a multi-system suppurative disease caused by Burkholderia pseudomallei, a soil saprophyte endemic in South East Asian countries

  • We describe the successful treatment outcome in a Diabetic with melioidosis pneumonia in this context

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Summary

Introduction

Melioidosis is a multi-system suppurative disease caused by Burkholderia pseudomallei, a soil saprophyte endemic in South East Asian countries. A 45-year-old Diabetic male was admitted under the department of Pulmonary Medicine, JIPMER, with complaints of fever, cough with expectoration, and breathlessness of 1-month duration. He had a history of loss of weight of 3 kg over 1-month duration. Cough was productive with copious yellowish non-foul smelling expectoration He had MMRC Grade IV dyspnoea and required Oxygen supplementation. Bronchial wash pyogenic culture showed growth of Burkholderia pseudomallei His blood sugar level was brought to control with oral hypoglycemic agents. He was treated with injection Ceftazidime 2 g intravenous q8 hourly for three weeks for pulmonary melioidosis. At the time of final follow-up, patient was symptom-free, chest radiology showed complete resolution of lesions, and the patient had a weight gain of 3 kg

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